In vitro activity of TD-1792, a multivalent glycopeptide-cephalosporin antibiotic, against 377 strains of anaerobic bacteria and 34 strains of Corynebacterium species.

نویسندگان

  • Kerin L Tyrrell
  • Diane M Citron
  • Yumi A Warren
  • Ellie J C Goldstein
چکیده

TD-1792 is a multivalent glycopeptide-cephalosporin heterodimer antibiotic with potent activity against Gram-positive bacteria. We tested TD-1792 against 377 anaerobes and 34 strains of Corynebacterium species. Against nearly all Gram-positive strains, TD-1792 had an MIC₉₀ of 0.25 μg/ml and was typically 3 to 7 dilutions more active than vancomycin and daptomycin.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 56 4  شماره 

صفحات  -

تاریخ انتشار 2012